Angiotensin II in Decompensated Cirrhosis Complicated by Septic Shock-Reference-Cited by-同舟云学术

Angiotensin II in Decompensated Cirrhosis Complicated by Septic Shock

Published:2019-09-20 Issue:3 Volume:24 Page:266-272
ISSN:1089-2532
Container-title:Seminars in Cardiothoracic and Vascular Anesthesia
language:en
Short-container-title:Semin Cardiothorac Vasc Anesth

Author:

Coleman Patrick J.¹,Nissen Alexander P.¹,Kim Daniel E.²³^ORCID,Ainsworth Craig R.²,McCurdy Michael T.⁴^ORCID,Mazzeffi Michael A.⁴,Chow Jonathan H.⁴^ORCID

Affiliation:

1. San Antonio Military Medical Center, Fort Sam Houston, TX, USA

2. US Army Institute of Surgical Research, Fort Sam Houston, TX, USA

3. Uniformed Services University of the Health Sciences, Bethesda, MD, USA

4. University of Maryland School of Medicine, Baltimore, MD, USA

Abstract

This case describes the first reported use of human-derived synthetic angiotensin II (Ang-2) in a patient with decompensated cirrhosis and septic shock. The patient presented in vasodilatory shock from Enterobacter cloacae bacteremia with a Sequential Organ Failure Assessment Score of 14 and a Model for End-Stage Liver Disease score of 36. This case is significant because liver failure was an exclusion criterion in the Angiotensin II for the Treatment of Vasodilatory Shock (ATHOS-3) trial, but the liver produces angiotensinogen, which is key precursor to Ang-2 in the renin-angiotensin-aldosterone system. Resuscitation with Ang-2 is a potentially beneficial medication when conventional vasopressors have failed to control mean arterial pressure in this population.

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Cardiology and Cardiovascular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1089253219877876

Reference45 articles.

1. Management of the critically ill patient with cirrhosis: A multidisciplinary perspective

2. Critical care management of the patient with cirrhosis awaiting liver transplant in the intensive care unit

3. Relative adrenal insufficiency in decompensated cirrhosis: Relationship to short-term risk of severe sepsis, hepatorenal syndrome, and death

4. Update on adrenal insufficiency in patients with liver cirrhosis

5. Vasopressin Deficiency and Vasodilatory State in End-Stage Liver Disease

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