Transrectal Elastographic Biopsy and Contrast-Enhanced Transrectal Biopsy May Offer Improvements Over the Current Transrectal Systemic Biopsy Technique

Abstract

Prostate cancer is a common cause of cancer-related death of men in the United States. The purpose of this review is to compare the validity of transrectal ultrasound–guided systemic biopsy with contrast-enhanced transrectal ultrasound–guided systemic biopsy and transrectal elastography–guided systemic biopsy for the detection of prostate cancer. Adding contrast-enhanced or transrectal elastography core targeting to transrectal ultrasound–guided biopsy is a feasible approach to increase detection rates of higher-grade prostate cancers. Because contrast-enhanced imaging of the prostate is not approved for use in the United States, elastography is the most effective sonographic solution to improve prostate cancer detection with current screening techniques.