Spectral features based convolutional neural network for accurate and prompt identification of schizophrenic patients

Abstract

Schizophrenia is a fatal mental disorder, which affects millions of people globally by the disturbance in their thinking, feeling and behaviour. In the age of the internet of things assisted with cloud computing and machine learning techniques, the computer-aided diagnosis of schizophrenia is essentially required to provide its patients with an opportunity to own a better quality of life. In this context, the present paper proposes a spectral features based convolutional neural network (CNN) model for accurate identification of schizophrenic patients using spectral analysis of multichannel EEG signals in real-time. This model processes acquired EEG signals with filtering, segmentation and conversion into frequency domain. Then, given frequency domain segments are divided into six distinct spectral bands like delta, theta-1, theta-2, alpha, beta and gamma. The spectral features including mean spectral amplitude, spectral power and Hjorth descriptors (Activity, Mobility and Complexity) are extracted from each band. These features are independently fed to the proposed spectral features-based CNN and long short-term memory network (LSTM) models for classification. This work also makes use of raw time-domain and frequency-domain EEG segments for classification using temporal CNN and spectral CNN models of same architectures respectively. The overall analysis of simulation results of all models exhibits that the proposed spectral features based CNN model is an efficient technique for accurate and prompt identification of schizophrenic patients among healthy individuals with average classification accuracies of 94.08% and 98.56% for two different datasets with optimally small classification time.