A Surgical Case of Inflammatory Myofibroblastic Tumor of the Liver: Potentially Characteristic Gross Features

Author:

Watanabe Jiro1,Yamada Sohsuke12ORCID,Sasaguri Yasuyuki13,Guo Xin2,Kurose Nozomu2ORCID,Kitada Kouji4,Inagaki Masaru4,Iwagaki Hiromi4

Affiliation:

1. Laboratory of Pathology, National Hospital Organization, Fukuyama Medical Center, Fukuyama, Japan

2. Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan

3. Laboratory of Pathology, Fukuoka Tokushukai Hospital, Fukuoka, Japan

4. Department of Surgery, National Hospital Organization, Fukuyama Medical Center, Fukuyama, Japan

Abstract

We herein reported a very rare surgical case of inflammatory myofibroblastic tumor (IMT) of the liver, showing potentially unique and specific gross findings on its cut surface: our IMT demonstrated a relatively well-demarcated and partly infiltrative and likely extrahepatic (ie serosal) but not intrahepatic mass, appearing firm and hemorrhagic, and yellow-whitish in color. The patient, who was a woman in her early 70s with 2-year follow-up for lung cryptococcosis and traffic accident, incidentally presented with unenhanced and low-density, heterogeneous mass on abdominal dynamic CT in the peripheral right lobe of the liver. We could conclusively diagnose the current lesion as the hepatic IMT after thorough analyses including a wide panel of immunohistochemical antibodies. Despite that, all clinicians and pathologists should be aware that the potentially characteristic, extrahepatic gross feature of IMT of the liver might also be one of the powerful supplementary tools for reaching its correct diagnosis. One of our aims in the presented case report is to emphasize that the hepatic IMT should be considered clinicopathologically in the differential diagnosis of mass lesions on the liver.

Funder

Fund of National Hospital Organization, Fukuyama Medical Center, Fukuyama, Japan

Publisher

SAGE Publications

Subject

Oncology

Reference5 articles.

1. Miettinen M, Fletcher CDM, Kindblom LG, Zimmermann A, Tsui WMS. WHO Classification of Tumours of the Digestive System (Mesenchymal tumours of the liver). Lyon, France: IARC Press; 2010:246.

2. Inflammatory Myofibroblastic Tumor of the Liver: A Cohort Study

3. Inflammatory myofibroblastic tumors

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