Usefulness of Chest and Skeletal Survey to Assess the Time of Relapse in Breast Cancer

Author:

Tesoro-Tess John David1,Valagussa Pinuccia1,Gardani Gianstefano2,Rossi Anna1,Tancini Gabriele1,Bajetta Emilio1,Marchini Silvana1,Uslenghi Carlo1

Affiliation:

1. Istituto Nazionale per lo Studio e la Cura del Tumori, Milano

2. Istituto di Scienze Radiologiche, Università, Milano

Abstract

The pertinent radiographs of 151 patients treated with radical mastectomy who showed relapse in the chest and/or in the skeleton as first site were reevaluated. Diagnostic accuracy was calculated by comparing the first examination considered as positive with the previous ones reported as negative. For chest lesions the accuracy was 80 % (70 % for parenchymal nodular densities), with no difference between symptomatic and asymptomatic patients. For bone metastases retrospective evaluation confirmed the radiological report (i.e., the time of relapse), in 73.8 %, with a value of 89.7 % in symptomatic and 53.4 % in asymptomatic patients. The site of involvement and morphological characteristics of the lesions did not influence the diagnostic accuracy. Therefore chest examination and, for symptomatic patients, radiographic bone survey still represent a useful modality to assess the diffusion of breast cancer. For asymptomatic patients other modalities, such as bone scan and biochemical tests, should be utilized.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

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