Cancer precision medicine today: Towards omic information in healthcare systems

Author:

Maggi Norbert1,Gazzarata Roberta2,Ruggiero Carmelina12,Lombardo Claudio34,Giacomini Mauro125

Affiliation:

1. Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genova, Genova, Italy

2. Healthropy s.r.l., Savona, Italy

3. Sos Europe s.r.l., Genova, Italy

4. Organisation of European Cancer Institutes–European Economic Interest Grouping, Brussels, Belgium

5. Centre of Excellence for the study of molecular mechanisms involved in cell-to-cell communication: from basic research to the clinic (CEBR), Genova, Italy

Abstract

Introduction: This article focuses on the integration of omics data in electronic health records and on interoperability aspects relating to big data analysis for precision medicine. Methods: Omics data integration methods for electronic health record and for systems interoperability are considered, with special reference to the high number of specific software tools used to manage different aspects of patient treatment. This is an important barrier against the use of this integrated approach in daily clinical routine. Results: The correct use of all three levels of interoperability (technical, semantic, and process interoperability) plays a key role in order to achieve an easy access to a significant amount of data, all with correct contextualization, which is the only way to obtain a real value from data for precision medicine. Conclusions: The proposed architecture could improve the potentialities of data routinely collected in many health information systems to form a real patient center information environment.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

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