Affiliation:
1. Operative Unit of Medical Oncology, Istituto Oncologico Veneto, Padua, Italy
Abstract
Aims and background Patients included in clinical trials are “selected”, and they usually differ from those commonly treated. Methods: From 1999 to 2004, in the Medical Oncology Department of Padua (Italy), 70 metastatic colorectal cancers were treated with FOLFOX4. Results Our results, compared with those of the registration trial (response rate, duration of response and progression-free survival) appeared lower; overall survival was improved. Conclusions The number of therapeutic regimens more than their type influenced the results.
Subject
Cancer Research,Oncology,General Medicine