Hyperfunctioning Adenoma of the Thyroid. Diagnostic Use of Radioiodine

Abstract

The clinical and pathological features of 8 cases of hyperfunctioning thyroid adenoma which underwent surgery are reported. All the cases were abserved in an early evolution stade. The diagnostic use of radioiodine (1131), alone or with T.S.H. stimulation or T3 inibition test, as well as histologic and radioautographic finding are described. Hyperfunctioning nodes show the histologic structure of simple or hyperplastic follicular adenoma, as well as the structure of foetal adenoma. Radioautography shows evidence of selective adenomatous tissue avidity for radioiodine, which is stored in the colloid. Adenoma arises in normal or in goitrous gland. Involution and loss of radioiodine avidity of neighbouring thyroid tissue were always found.