Immunohistochemical Study of Ten Cases of Argyrophilic Carcinoma (Carcinoid) of the Breast-Reference-Cited by-同舟云学术

Immunohistochemical Study of Ten Cases of Argyrophilic Carcinoma (Carcinoid) of the Breast

Published:1988-06 Issue:3 Volume:74 Page:295-302
ISSN:0300-8916
Container-title:Tumori Journal
language:en
Short-container-title:Tumori

Author:

Andreola Salvatore¹,Di Re Emanuela²,Merson Mirella³,Maggiulli Lorenza²,De Palma Patrizia⁴

Affiliation:

1. Divisioni di Anatomia Patologica e Citologia

2. Oncologia Chirurgica G, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano

3. Oncologia Chirurgica B, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano

4. Ospedale di Termoli

Abstract

The significance of argyrophilia in human breast cancer is still a controversial issue. We tested immunohistochemically 10 cases of argyrophilic carcinomas of the breast and found evidence of immunoreactivity with neuroendocrine markers: chromogranin, NSE, gastrin, insulin and bombesin. Argyrophilia was demonstrated in breast cancers of the usual types and was found to be related to the secretory activity of neoplastic cells. Unfortunately, no adequate follow-up data are available to clarify the natural history of argyrophilic breast cancer. A clinical treatment different from that of conventional breast cancer is not at present justified.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030089168807400309

Reference35 articles.

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2. Ectopic Production of Human Chorionic Gonadotrophin by Human Breast Tumours

3. Endocrine Markers in Argyrophilic Carcinomas of the Breast

4. Endocrine differentiation in mucoid carcinoma of the breast

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