Electronic cigarette, or vaping, product use-associated lung injury (EVALI) in a patient with testicular cancer: A case report

Author:

Stein Jacob1,Kay Hannah E2ORCID,Sites Jeremy3,Pirzadeh Afsaneh3,Joyner Benny L3,Darville Toni4,Bjurlin Marc A2,Rose Tracy L1,Jaspers Ilona5,Milowsky Matthew I1

Affiliation:

1. Department of Medicine, Division of Hematology/Oncology, UNC Chapel Hill, Chapel Hill, NC, USA

2. Department of Urology, UNC Chapel Hill, Chapel Hill, NC, USA

3. Department of Pediatrics, Division of Pediatric Critical Care Medicine, UNC Chapel Hill, Chapel Hill, NC, USA

4. Department of Pediatrics, Division of Pediatric Infectious Disease, UNC Chapel Hill, Chapel Hill, NC, USA

5. Department of Pediatrics, Division of Microbiology and Immunology, UNC Chapel Hill, Chapel Hill, NC, USA

Abstract

Electronic cigarette, or vaping, product use-associated lung injury (EVALI) is an increasingly recognized entity with the potential for severe pulmonary toxicity. We present the case of a young man first evaluated at a tertiary care center in the United States in 2019 with newly diagnosed testicular cancer with acute respiratory failure, which was initially attributed to possible metastatic disease but eventually determined to be related to EVALI. This case highlights the clinical features of EVALI, the potential diagnostic dilemma that can arise with EVALI when occurring in the setting of malignancy and the importance of inquiring about vaping use among patients with malignancy, especially in adolescents and young adults.

Funder

National Cancer Institute

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

Reference10 articles.

1. Vaping-Associated Lung Injury: A Review

2. FDA. Respiratory illnesses associated with use of vaping products. US Food and Drug Administration. FDA, http://www.fda.gov/news-events/public-health-focus/lung-illnesses-associated-use-vaping-products (2020, accessed 2 February 2023).

3. Vaping and Lung Inflammation and Injury

4. Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Final Report

5. Analysis of Cannabinoid-Containing Fluids in Illicit Vaping Cartridges Recovered from Pulmonary Injury Patients: Identification of Vitamin E Acetate as a Major Diluent

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