Comportamento Elettroforetico di Estratti di Sarcoma di Rous Sottoposti ad Ultracentrifugazione

Abstract

Results are referred on the electrophoretic behaviour of Rous sarcoma extracts. The supernatant obtained by serial centrifugations of the extracts (some of which at high speedness) has six components with the following mobilities: 10,3; 8,3; 6,5; 4,5; 2,3; and 0,4 × 10−5 cm2 volt−1sec−1. Such components are respectively: polysaccharidic acids, nucleic acids, nucleoproteins, albumins, globulins and hemogloblin. The experiments carried out for the study of the infectiousness showed that the tumor induction is correlated with the fraction which may be separated by electrophoresis and is characterized by the ultraviolet spectrum of nucleic substances.