Biochimica Dei Tessuti Iperplastici: Modificazioni Del Metabolismo Cellulare Indotte Dalla Rigenerazione Epatica

Abstract

The dynamic cell processes connected with liver regeneration have been studied as follows: 1) ribonucleic and desoxyribonucleic contents; 2) transamination reactions (glutamic-oxalacetic transaminase and glutamic-piruvic transaminase); 3) reactions related to the peptides constitution and demolition (dipeptidase); 4) reactions involved in the hydrolytic release of phosphoric bounds (alkaline phosphomonoesterase, acid pyrophosphatase, gluco-6-phosphatase); 5) reactions entering in nucleotides splitting and formation (nucleotidase). It has been particularly observed that the metabolic differences between normal and regenerating liver are mainly quantitative and that the enhancement of proteosynthesis does not necessarily imply a simultaneous enhancement of all the related biochemical activities.