Primary Spinal Epidural Non-Hodgkin's Lymphoma the Contribution of Nuclear Magnetic Resonance Imaging, Therapeutic Approach and Review of the Literature

Author:

Ron llan G.1,Reider Irith2,Wigler Nelly1,Chaitchik Samario1

Affiliation:

1. Department of Oncology, Tel-Aviv Sourasky Medical Centre, Sackler Faculty of Medicine, Tel-Aviv University, Israel

2. Neuroradiology Unit, Tel-Aviv Sourasky Medical Centre, Sackler Faculty of Medicine, Tel-Aviv University, Israel

Abstract

Primary spinal epidural lymphoma (Stage I) is diagnosed predominantly late after a long prodromal phase of local back pain resulting in spinal cord compression. The use of CT and NMR images in the early stage of investigation and their analysis may help to diagnose these cases prior to the appearance of neurologic deficit. We report on 2 patients who presented with prolonged localized back pain with sudden symptoms of spinal cord compression. CAT scan and NMR imaging demonstrated the characteristic appearance of lymphoma. Decompressive laminectomy supported the diagnosis. Radiotherapy treatment to the region of the non-Hodgkin's lymphoma resulted in complete resolution. Thereafter, systemic chemotherapy with CHOP achieved a good response.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

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