Enhancement of Pulmonary Metastases following the Intravenous Infusion of a Suspension of Ellagic Acid

Abstract

The intravenous injection of a suspension of ellagic acid increased pulmonary metastases from 33 per-cent in the controls to 85 per-cent in the ellagic acid (EA) treated rats. A significant shortening of the silicone and glass clotting times, and a reduction in bleeding following the partial amputation of the tail was also observed after the infusion of EA. There was no obvious untoward side effect of EA in any of the animals studied in these series.