Ewing's Sarcoma: An Approach to Radiological Diagnosis

Author:

Lombardi Fabrizio1,Gasparini Marco1,Gianni Cristina1,Petrillo Raffaele1,Tesoro-Tess John David1,Volterrani Fabio1,Musumeci Renato1

Affiliation:

1. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano

Abstract

All the pertinent radiographs of 83 patients with histologically proven Ewing's sarcoma were reviewed. Forty-nine patients were in the pediatric age group, and 34 were adults. The mean age, the symptoms and time from symptoms to diagnosis were evaluated in the 2 groups. The site of primary involvement was in 54 % the long bones, 35 % the flat bones, 8 % the small bones and 3 % extraosseous. For the primary site we considered the diagnostic results of the standard radiographic investigations and in some cases the usefulness of angiography, xeroradiography and telethermography. At presentation we also evaluated the possible diffusion of the disease with standard radiographic surveys (chest and skeletal, including limbs) and with foot lymphography in selected cases. In this way, 57 patients (69 %) were considered to have localized disease. In this group, we also considered the value of the periodic radiographic follow-up, which enabled us to disclose the appearance of metastases (chest 64 %, bone 54 %, lymph nodes 11 %) in 28 cases (49 %). Finally, we made a comparison of the different radiologic and epidemiologic findings between children and adults.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Ewing Sarcoma;Diagnostic Imaging: Pediatrics;2017

2. Atypical growth on MRI in a case of Ewing’s sarcoma despite lower SUV on PET;Skeletal Radiology;2013-12-19

3. Follow-up of musculoskeletal tumours;European Radiology;1999-02-24

4. Knochentumoren;Kinderradiologie 1;1996

5. Knochentumoren;Kinderradiologie 1;1990

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