The Outcome of Wilms’ Tumor in Infants, Italy 1970-79

Author:

Pastore G.1,Di Montezemolo L. Cordero1,Del Prever A. Brach1,Bartolozzi G.2,Carli M.3,Castello M.4,Ceci A.5,Fossati-Bellani F.6,Guazzelli C.2,Curto M. Lo7,Madon E.1,Marchi A.8,Massolo F.9,Mori P.G.10,Paolucci G.11,Pianca C.12,Rosati M.12,Tamaro P.13

Affiliation:

1. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Torino

2. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Firenze

3. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Padova

4. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Roma

5. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Bari

6. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano;

7. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Palermo

8. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Pavia

9. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Modena

10. Istituto G. Gaslini, Genova;

11. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Bologna

12. Ospedale Bambin Gesù, Roma)

13. The Italian Study Group on Wilms’ Tumor; Cliniche Pediatriche delle Università di, Trieste;

Abstract

Thirty-four infants under 1 year of age with Wilms’ tumor were diagnosed and treated in 14 Italian pediatric oncology units during 1970-79. The 3-year survival rates decreased with higher group unilateral tumors: 95% in group I Wilms’ tumor, 75% in group II and 20% in group III. The survival rates for children with group I and II Wilms’ tumor were similar for those who were treated with surgery and chemotherapy and those who also received postoperative radiotherapy. During 1975-79 fewer patients with group I Wilms’ tumor received radiotherapy (1 of 11) than during 1970-74 (4 of 6, p < 0.05). All these children are alive at this writing.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

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