Cholestatic Liver Disease with Ductopenia (Vanishing Bile Duct Syndrome) in Hodgkin's Disease: Report of a Case-Reference-Cited by-同舟云学术

Cholestatic Liver Disease with Ductopenia (Vanishing Bile Duct Syndrome) in Hodgkin's Disease: Report of a Case

Published:2004-09 Issue:5 Volume:90 Page:517-520
ISSN:0300-8916
Container-title:Tumori Journal
language:en
Short-container-title:Tumori

Author:

Guliter Sefa¹,Erdem Ozlem²,Isik Mine³,Yamac Kadri³,Uluoglu Omer²

Affiliation:

1. University of Kirikkale, Faculty of Medicine, Department of Gastroenterology, Kirikkale, Turkey

2. Gazi University, Faculty of Medicine, Department of Pathology, Turkey

3. Department of Hematology, Ankara, Turkey

Abstract

Liver involvement is common in advanced stages of Hodgkin's disease. However, only a small percentage of patients with Hodgkin's disease develops jaundice due to several causes. Vanishing bile duct syndrome secondary to Hodgkin's disease is a rare cause of cholestasis in these patients. Only 20, cases, to our knowledge, have been reported so far in adults. We report a case of Hodgkin's disease presenting with obstructive jaundice without detectable liver involvement. Liver biopsies revealed intrahepatic cholestasis and ductopenia. Although the patient was given chemotherapy, he died of sepsis and disseminated intravascular coagulation after 24 weeks of admission to hospital.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030089160409000516

Reference24 articles.

1. Diagnosis of liver involvement by lymphoma: Results in 96 consecutive peritoneoscopies

2. Jaundice in Hodgkin's disease

3. Differential Diagnosis of Jaundice in Lymphoma Patients

4. Cholestasis Associated With Extrabiliary Hodgkin’s Disease

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