Fosinopril Overdose in an Infant

Author:

Stokes Kimberly A,Lanski Steven L,Leikin Jerrold B

Abstract

Objective: To report an accidental fosinopril overdose in an infant. Case Summary: A 20-month-old African-American girl ingested approximately 16 mg/kg of fosinopril. Following aggressive gastric decontamination, the patient experienced an uneventful hospital course. Discussion: This appears to be the first report of accidental fosinopril ingestion in an infant. Virtually no adverse effects were noted after an ingestion that was approximately 10 times a therapeutic adult dose. It seems that fosinopril toxicity was minimal in the accidental overdose following early gastric decontamination (within 1 h of ingestion). Conclusions: Observation of vital signs with no invasive procedures appears to be the primary treatment method following early gastric decontamination for an accidental fosinopril overdose in an infant.

Publisher

SAGE Publications

Subject

Pharmaceutical Science

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4. Lisinopril Overdose and Management with Intravenous Angiotensin II

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