Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single‐arm efficacy-Reference-Cited by-同舟云学术

Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single‐arm efficacy

Published:2021-10 Issue:4 Volume:11 Page:1-12
ISSN:2045-8940
Container-title:Pulmonary Circulation
language:en
Short-container-title:Pulm. circ.

Author:

Wilkins Martin R.¹^ORCID,Mckie Mikel A.²,Law Martin²^ORCID,Roussakis Andreas A.¹^ORCID,Harbaum Lars¹,Church Colin³⁴,Coghlan J Gerry⁵,Condliffe Robin⁶⁷,Howard Luke S⁸,Kiely David G⁶⁷,Lordan Jim⁹,Rothman Alexander⁶⁷^ORCID,Suntharalingam Jay¹⁰,Toshner Mark¹¹¹²^ORCID,Wort Stephen J¹³,Villar Sofía S.²

Affiliation:

1. National Heart and Lung InstituteFaculty of MedicineImperial College LondonHammersmith HospitalLondonUK

2. MRC Biostatistics UnitSchool of Clinical MedicineCambridge Institute of Public HealthCambridgeUK

3. Golden Jubilee National HospitalNHS Greater Glasgow and ClydeClydebankUK

4. Golden Jubilee National HospitalUniversity of GlasgowScotlandUK

5. Royal Free HospitalRoyal Free London NHS Foundation TrustLondonUK

6. Department of InfectionImmunity and Cardiovascular DiseaseUniversity of SheffieldSheffieldUK

7. Sheffield Pulmonary Vascular Disease UnitSheffield Teaching Hospitals NHS Foundation TrustSheffieldUK

8. National Pulmonary Hypertension ServiceHammersmith HospitalImperial College Healthcare NHS TrustLondonUK

9. Newcastle Freeman HospitalFreeman Road, High HeatonNewcastle Upon TyneUK

10. Royal United HospitalRoyal United Hospitals Bath NHS Foundation TrustBathUK

11. Heart Lung Research InstituteUniversity of CambridgeCambridgeUK

12. Department of MedicineUniversity of CambridgeCambridgeUK

13. Royal Brompton HospitalGuy’s and St Thomas’s TrustLondonUK

Funder

British Heart Foundation

Efficacy and Mechanism Evaluation Programme

Medical Research Council

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1177/20458940211052823

Reference37 articles.

1. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).;Galiè N;Eur Heart J,2016

2. A global view of pulmonary hypertension;Hoeper MM;Lancet Respir Med,2016

3. Epidemiology and treatment of pulmonary arterial hypertension.;Lau EMT;Nat Rev Cardiol,2017

4. Modern age pathology of pulmonary arterial hypertension.;Stacher E;Am J Respir Crit Care Med,2012

5. NHS UK. National PH Audit. 2019 [2/10/2020]. Available from:https://digital.nhs.uk/data‐and‐information/publications/statistical/national‐pulmonary‐hypertension‐audit/2019.

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanisms and treatment of pulmonary arterial hypertension;Nature Reviews Cardiology;2024-08-07

2. A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension;Experimental Cell Research;2024-08

3. C-type natriuretic peptide/cGMP/FoxO3 signaling attenuates hyperproliferation of pericytes from patients with pulmonary arterial hypertension;Communications Biology;2024-06-06

4. Current Management and Future Directions for Pulmonary Arterial Hypertension Associated with Congenital Heart Disease;Journal of Personalized Medicine;2023-12-20

5. Treatment of pulmonary arterial hypertension: recent progress and a look to the future;The Lancet Respiratory Medicine;2023-09