Safety, tolerability, and pharmacokinetics of the selective prostacyclin receptor agonist ralinepag in single and multiple dosing studies of an immediate‐release oral formulation in healthy volunteers-Reference-Cited by-同舟云学术

Safety, tolerability, and pharmacokinetics of the selective prostacyclin receptor agonist ralinepag in single and multiple dosing studies of an immediate‐release oral formulation in healthy volunteers

Published:2020-04 Issue:2 Volume:10 Page:1-13
ISSN:2045-8940
Container-title:Pulmonary Circulation
language:en
Short-container-title:Pulm. circ.

Author:

Grundy John S.¹,King Christopher D.¹,Adams John W.²,Cabell Christopher H.³

Affiliation:

1. Nonclinical Development & Clinical Pharmacology DepartmentArena Pharmaceuticals, Inc.San DiegoCAUSA

2. Research DepartmentArena Pharmaceuticals, Inc.San DiegoCAUSA

3. Clinical Development DepartmentArena Pharmaceuticals, Inc.San DiegoCAUSA

Funder

United Therapeutics Corporation

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1177/2045894020922814

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3. The endothelin system in pulmonary arterial hypertension;Galié N;Cardiovasc Res,2004

4. Practical considerations for therapies targeting the prostacyclin pathway;Farber HW;Eur Respir Rev,2016

5. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled trial;Galie N;J Am Coll Cardiol,2002

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2. Emerging pharmacotherapies for the treatment of pulmonary arterial hypertension;Expert Opinion on Investigational Drugs;2023-10-30

3. Medical Management of Pulmonary Arterial Hypertension: Current Approaches and Investigational Drugs;Pharmaceutics;2023-05-24

4. Efficacy and safety of non-prostanoid prostacyclin receptor agonist for pulmonary hypertension: A meta-analysis;Pulmonary Pharmacology & Therapeutics;2023-02