Spontaneous Ovarian Choriocarcinoma, Yolk Sac Carcinoma, and Teratoma in B6C3F1 Mice: A Case Report-Reference-Cited by-同舟云学术

Spontaneous Ovarian Choriocarcinoma, Yolk Sac Carcinoma, and Teratoma in B6C3F1 Mice: A Case Report

Published:1993-01 Issue:1 Volume:21 Page:91-98
ISSN:0192-6233
Container-title:Toxicologic Pathology
language:en
Short-container-title:Toxicol Pathol

Author:

Frith Charles H.¹,Evans Mark G.²

Affiliation:

1. Toxicology Pathology Associates, 1102 Briar Creek Road, Little Rock, Arkansas 72211, and Department of Pathology and Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205

2. Department of Pathology, International Research and Development Corporation, 500 North Main, Mattawan, Michigan 49071

Abstract

Three ovarian neoplasms (choriocarcinoma, yolk sac carcinoma, and teratoma) were diagnosed in a 2 yr carcinogenicity study involving B6C3F1 mice. The yolk sac carcinoma and the teratoma occurred in opposite ovaries of a single female mouse that was sacrificed in extremis on study day 725. The choriocarcinoma occurred in a female mouse that was sacrificed in extremis on study day 565. These neoplasms were considered to be spontaneous in origin.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/019262339302100112

Reference12 articles.

1. Ovarian Choriocarcinoma in the Mouse

2. Ovarian neoplasms in F344 rats and B6C3F1 mice.

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