Measurement of 14 Blood Components in Rats, Dogs, and Mice Using CentrifichemR Analyzer

Author:

Chin B. H.1,Kozbelt S. J.2,Sullivan L. J.2

Affiliation:

1. Diamond Shamrock Corporation Department of Safety Assessment T. R. Evans Research Center P. O. Box 348 Painesville, OH 44077

2. Carnegie-Mellon University Carnegie-Mellon institute of Research Chemical Hygiene Fellowship 4400 Fifth Avenue Pittsburgh, PA 15213

Abstract

Methods for determining 14 blood chemistry parameters in dogs, mice, and rats were established using an automated centrifugal analyzer methodologies for human samples. The precision of each method was determined to be satisfactory with the exception of the following; albumin and alanine aminotransferase in mice and creatinine in dogs. Based on these methods, normal values for 14 tests in these species were compiled.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

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