Affiliation:
1. R. J. Reynolds Tobacco Company, Research & Development, Bowman Gray Technical Center, P.O. Box 1487, Winston-Salem, North Carolina 27102
Abstract
Scientific information on environmental tobacco smoke (ETS) is critically reviewed. Key areas addressed are: differences in chemical composition between mainstream smoke, sidestream smoke, and ETS; techniques for measurement of ETS; epidemiology; in vitro and in vivo toxicology; and chamber and field studies of perceptual or physiological effects. Questions concerning estimation of ETS exposure, suitability of various biomarkers, calculation of lifetime dose, control of confounding variables, use of meta-analysis, and the relationship between ETS concentrations and human responses all emphasize the need for additional research in order to assess potential effects of ETS on health or comfort.
Subject
Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine
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