Incidence and Pathology of Spontaneous Renal Pelvis Transitional Cell Carcinomas in Rats-Reference-Cited by-同舟云学术

Incidence and Pathology of Spontaneous Renal Pelvis Transitional Cell Carcinomas in Rats

Published:1991-04 Issue:3 Volume:19 Page:287-289
ISSN:0192-6233
Container-title:Toxicologic Pathology
language:en
Short-container-title:Toxicol Pathol

Author:

Chandra Manik¹,Riley Michael G.I.¹,Johnson Dale E.¹

Affiliation:

1. American Cyanamid Company, Wilbur G. Malcolm Toxicology Laboratory, Pearl River, New York 10965

Abstract

Spontaneous transitional cell carcinoma (TCC) originating from renal pelvis is very rare. Metastasis from this tumor having been reported only once previously. Data from control groups of 17 carcinogenicity studies in Sprague-Dawley and 10 carcinogenicity studies in Fischer 344 (F-344) rats were reviewed and evaluated to determine the incidence and pathology of TCC. Renal pelvis TCC were observed in 1 male and 1 female Sprague-Dawley rat and in 1 male F-344 rat. Metastatis from TCC to the lung was observed in 1 male Sprague-Dawley rat. Detailed histopathological features of this tumor are described and discussed.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/019262339101900312

Reference8 articles.

1. Urothelial Carcinoma of the Kidney and Ureter

2. Incidence Patterns of Spontaneous Tumors in BN/Bi Rats

3. Spontaneous renal pelvic tumor in an aged rat.

4. The Urinary System

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