Ectopic Thyroid in the Aortic Valve of a Han Wistar Rat-Reference-Cited by-同舟云学术

Ectopic Thyroid in the Aortic Valve of a Han Wistar Rat

Published:2010-01-25 Issue:2 Volume:38 Page:312-314
ISSN:0192-6233
Container-title:Toxicologic Pathology
language:en
Short-container-title:Toxicol Pathol

Author:

Baudimont Fannie¹,Booler Helen²,Casey Tony²,Heier Annabelle²

Affiliation:

1. Ecole Nationale Vétérinaire de Nantes—Unité d’Anatomie Pathologique, Atlantopôle La Chantrerie, Nantes Cedex, France

2. AstraZeneca—Safety Assessment, Mereside Alderley Park, Macclesfield, Cheshire, United Kingdom

Abstract

Histological examination of the heart of a clinically normal, 10-week-old female Han Wistar rat revealed a 600 × 400-μm mass of ectopic thyroid tissue within the subendothelial connective tissue of the aortic valve. The mass protruded into the left ventricular lumen and was composed of single layers of cuboidal to low-columnar epithelium organized into follicles often containing colloid. Parafollicular cells were not evident. To the authors' knowledge, this is the first report of intracardiac ectopic thyroid gland in the rat and the first report of ectopic thyroid within a heart valve in a mammal.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0192623309357952

Reference18 articles.

1. Intracardiac Ectopic Thyroid Carcinosarcoma in a Dog

2. Arteries define the position of the thyroid gland during its developmental relocalisation

3. The Endocrine System

4. Ectopic Thyroid Carcinoma Causing Right Ventricular Outflow Tract Obstruction in a Dog

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2. Clinical Features and Treatment Outcomes of 41 Dogs with Sublingual Ectopic Thyroid Neoplasia;Journal of Veterinary Internal Medicine;2014-07-23

3. Ectopic thyroid tissue in the periaortic area, cardiac cavity and aortic valve in a Beagle dog – A case report;Experimental and Toxicologic Pathology;2012-03