Adverse Reactions to St John's Wort-Reference-Cited by-同舟云学术

Adverse Reactions to St John's Wort

Published:2001-02 Issue:1 Volume:46 Page:77-79
ISSN:0706-7437
Container-title:The Canadian Journal of Psychiatry
language:en
Short-container-title:Can J Psychiatry

Author:

Parker Vivien¹,Wong Al bert HC²,Boon Heather S³,Seeman Mary V⁴

Affiliation:

1. StaffPsy chia trist, De part ment ofPsy chia try, Fac ultyofMedi cine, Uni versity of To ronto, To ronto, On tario

2. Fel low, De part ment ofPsy chia try, Fac ulty ofMedi cine, Uni ver sity ofToronto, To ronto, On tario

3. As sis tant Pro fes sor, De partmentofHealthAdministration, Fac ulty ofMedi cine, Univer sity ofTo ronto, To ronto, On tario

4. Pro fes sor Emeri tus, De part ment ofPsy chia try, Fac ulty ofMedi cine, Univer sity ofTo ronto, To ronto, On tario

Abstract

Objective: To re port 2 cases of ad verse re ac tions to St John's wort, a pop u lar herbal treat ment for de pression. Method: We pres ent 2 case his to ries and re view the ex ist ing lit er a ture re gard ing St John's wort. Results: St John's wort may cause se ro to nin syn drome in sen si tive pa tients. In ad di tion, St John's wort may be as so ci ated with hair loss. Conclusions: For clin i cal rea sons, it is im por tant to rec og nize and re port ad verse re ac tions to herbal rem e dies and to doc u ment that these treat ments have side ef fects com men su rate with their po tent ac tion on brain neurochemistry.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

Link

http://journals.sagepub.com/doi/pdf/10.1177/070674370104600112

Reference28 articles.

1. St John's wort for depression--an overview and meta-analysis of randomised clinical trials

2. Controlled Clinical Trials of Hypericum Extracts in Depressed Patients - an Overview

3. Inhibition of Monoamine Oxidase by Hypercin

4. Inhibition of MAO by Fractions and Constituents of Hypericum Extract

5. Inhibition of MAO and COMT by Hypericum Extracts and Hypericin

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