Clinical Guidelines for the Treatment of Depressive Disorders VI. Special Populations

Abstract

Background: The Canadian Psychiatric Association and the Canadian Network for Mood and Anxiety Treatments partnered to produce clinical guidelines for psychiatrists for the treatment of depressive disorders. Methods: A standard guidelines development process was followed. Relevant literature was identified using a computerized Medline search supplemented by review of bibliographies. Operational criteria were used to rate the quality of scientific evidence. and the line of treatment recommendations included consensus clinical opinion. This section, “Special Populations, ” is I of 7 articles that were drafted and reviewed by clinicians. Revised drafts underwent national and international expert peer review. Results: This section reports on the prevalence, course, and outcome of depression for specific populations. Psychological, pharmacologic, and other biological treatment options for these populations—children and adolescents, the elderly, women at times of increased risk within the reproductive cyde, and specific ethnocultural groups—are critically evaluated. Conclusions: Major depressive disorder (MDD) is prevalent across the lifespan. In general, clinical presentations are more similar than different across age, sex, and cultural divides. Although less evidence is available for the efficacy of treatments in these subpopulations than in mid-life patients, comparable rates of response for pharmacotherapies, electroconvulsive therapy (ECT), and, in some cases, evidence-based psychotherapies have been reported.