How Does Electroconvulsive Therapy Work? Theories on its Mechanism-Reference-Cited by-同舟云学术

How Does Electroconvulsive Therapy Work? Theories on its Mechanism

Published:2011-01 Issue:1 Volume:56 Page:13-18
ISSN:0706-7437
Container-title:The Canadian Journal of Psychiatry
language:fr
Short-container-title:Can J Psychiatry

Author:

Bolwig Tom G¹

Affiliation:

1. Emeritus Professor of Psychiatry, Department of Psychiatry, Copenhagen University Hospital, Copenhagen, Denmark

Abstract

This article reviews 3 current theories of electroconvulsive therapy (ECT). One theory points to generalized seizures as essential for the therapeutic efficacy of ECT. Another theory highlights the normalization of neuroendocrine dysfunction in melancholic depression as a result of ECT. A third theory is based on recent findings of increased hippocampal neurogenesis and synaptogenesis in experimental animals given electroconvulsive seizures. Presently, the endocrine theory has the strongest foundation to explain the working mechanism of ECT.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

Link

http://journals.sagepub.com/doi/pdf/10.1177/070674371105600104

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