Prevalence Ratio of HTLV-1 in Nursing Mothers From the State of Paraíba, Northeastern Brazil

Author:

Pimenta Flávia C. F.1,Kashima Haddad Simone2,de Medeiros João G.3,Costa Maria José C.4,Diniz Margareth F. M.5,Fernandes Melina P.6,de Araújo Lenisio B.7,Pombo-de-Oliveira Maria S.8

Affiliation:

1. Department of Pediatric Medicine, Federal University of Paraíba, João Pessoa, Brazil

2. Ribeirão Preto, São Paulo, Brazil

3. Pediatric Department, Federal University of Paraíba, João Pessoa, Brazil

4. Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, Brazil

5. Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, Brazil

6. Federal University of Paraíba, Brazil

7. Acute leukemia study group in Brazil, Department of Surgery, CCS, Federal University of Paraíba, João Pessoa, Brazil

8. Pediatric Leukemia and Lymphoma Group at the Divisão de Medicina Experimental, CPq, Instituto Nacional do Câncer, Rio de Janeiro, Brazil, @hotmail.com

Abstract

The human T-cell lymphotropic virus type 1 (HTLV-1) was the first human retrovirus known as a direct causal agent of a malignant disease. The vertical route of HTLV transmission is the most frequent pathway of the virus contamination. This study was performed to determine the prevalence ratio of HTLV-1 infection among nursing women. From January 2004 to January 2005, blood samples from 1033 nursing mothers from Paraíba, Brazil were evaluated for HTLV antibodies by ELISA and HTLV-1 viral particles confirmed by polymerase chain reaction (PCR). HTLV antibodies were detected in 7 women. The overall seroprevalence ratio was 0.68% and HTLV-1 viral sequences were confirmed by PCR in 2 women. These preliminary data suggest that HTLV screening should be introduced as a mandatory test before breastfeeding and breast milk donation in Paraíba, Brazil. Additionally, counseling programs would help reduce the prevalence ratio of HTLV-1 infected individuals in this Brazilian region. J Hum Lact. 24(3):289-292.

Publisher

SAGE Publications

Subject

Obstetrics and Gynecology

Reference23 articles.

1. Blattner WA, Pombo-de-Oliveira MS HTLV-1 and HTLV-1I. In: Merigan TC Jr, Barlett JG, Bolognesi D, eds. Textbook of AIDS in Medicine . 2nd ed. Baltimore, MD: Williams & Wilkins ; 1999:1003-1029.

2. A prospective study of transmission by transfusion of HTLV-I and risk factors associated with seroconversion

3. Male-to-Female Transmission of Human T-Cell Lymphotropic Virus Types I and II: Association with Viral Load

4. Recommendations for breastfeeding during maternal infections

5. Spastic paraparesis of obscure origin

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3