Development and evaluation of hydroxytite-based anti-microbial surface coatings on polydopamine-treated porous 3D-printed Ti6Al4V alloys for overall biofunctionality

Author:

Singh Gurmohan1ORCID,Saini Abhineet2,Pabla BS3

Affiliation:

1. Chitkara University School of Engineering and Technology, Chitkara University, Himachal Pradesh, India

2. Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, India

3. Department of Mechanical Engineering, National Institute of Technical Teacher Training and Research, Chandigarh, India

Abstract

The current investigation aims to develop hydroxyapatite-based biofunctional composite coatings on polydopamine-treated porous 3D-printed Ti6Al4V alloy implant specimens for orthopedic uses. The porous 3D-printed implants based on Ashby Gibson’s mathematical model for cellular materials are fabricated at a 65% level of porosity, so as to attain the mechanical strength of human bones. Further, the addition of strontium and silver in hydroxyapatite for improved biocompatibility of the 3D-printed implant to enhance its biofunctionality and its validation is performed. The resulting coated substrates are subjected to a series of morphological, elemental, phase, mechanical, and biological tests. When subjected to the uniaxial compression, the values for modulus of elasticity and yield strength of 3D-printed substrates are compared to the targeted value of elastic modulus and yield strength for the human bones (10–30 GPa and 148–240 MPa, respectively). The effect of polydopamine-treated 3D-printed Ti6Al4V substrates on the coating compositions of calcium and phosphorus has been compared to the untreated samples. The coating thickness and adhesion strength have been calculated and compared for different coating groups. All the samples, except untreated pure hydroxyapatite samples, displayed antimicrobial activity for both the gram-positive and gram-negative bacteria in the zone inhibition test. Hence, the current experiment provides a novel option to fabricate porous Ti6Al4V scaffolds, with a low-temperature surface coating to attain improved biofunctionality for orthopedic applications.

Funder

National Science and Technology Entrepreneurship Development Board

Publisher

SAGE Publications

Subject

Industrial and Manufacturing Engineering,Mechanical Engineering

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. From clinic to lab: Advances in porous titanium-based orthopedic implant research;Journal of Materials Research and Technology;2024-05

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