Botulinum Toxin to Improve the Prognosis of Skin Transplantation: A Short Narrative Review

Author:

Hu Xiangyan1,Liu Yang2,Yang Fengying1,Hu Weigang3ORCID,Sun Xifeng4

Affiliation:

1. Health Care Center, Shandong Sport University, Jinan, Shandong, China

2. Department of Anesthesiology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong Province, China

3. Department of Burns and Plastic Surgery, Yichang Central People's Hospital, Yichang, China

4. Department of Urology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China

Abstract

Skin transplantation is a traditional and well-established method of repairing skin loss, especially deep second-degree postburn wounds. Complications often happen amid the healing process, including necrosis and skin contracture, which has raised widespread concern from patients and doctors. Since the first recorded medical application of botulinum toxin for strabismus, accumulating evidence has enclosed all-round potential of botulinum toxin, more than aesthetic management. In recent decades, botulinum toxin also has been revealed to improve the prognosis of skin grafts. This literature review aims to briefly summarize the history and latest advances of its use for skin transplantation.

Funder

Natural Science Foundation of Shandong Province

Publisher

SAGE Publications

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