Future Research Directions in Sleep and ADHD

Author:

Owens Judith12,Gruber Reut34,Brown Thomas56,Corkum Penny78,Cortese Samuele9,O’Brien Louise10,Stein Mark11,Weiss Margaret12

Affiliation:

1. George Washington School of Medicine and Health Sciences, Washington, DC, USA

2. Children’s National Medical Center, Washington, DC, USA

3. McGill University, Montreal, Quebec, Canada

4. Douglas Hospital Research Centre, Montreal, Quebec, Canada

5. Yale University School of Medicine, New Haven, CT, USA

6. Yale Clinic for Attention and Related Disorders, New Haven, CT, USA

7. Dalhousie University, Halifax, Nova Scotia, Canada

8. IWK Health Centre, Halifax, Nova Scotia, Canada

9. New York University Child Study Center, New York City, USA

10. University of Michigan, Ann Arbor, USA

11. University of Illinois, Chicago, USA

12. University of British Columbia, Vancouver, Canada

Abstract

Objective: To explore relationships between basic and translational science research regarding sleep and ADHD in children. Method: A multidisciplinary group of experts in pediatric sleep medicine and ADHD convened in November 2010 to summarize the current literature, delineate knowledge gaps, and formulate recommendations regarding future research directions and priorities. Results: Six major research areas of interest were identified: (a) brain centers regulating sleep, arousal, and attention; (b) neurotransmitter systems involved in both sleep and attention regulation; (c) alterations of neural systems regulating sleep in ADHD; (d) phenotypic similarities between behavioral, mood, and cognitive manifestations of insufficient/disrupted sleep and ADHD; (e) hypoarousal and sleepiness in ADHD; and (f) external sleep–wake signals that affect sleep regulation in ADHD. Conclusion: An enhanced understanding of the complex mechanisms regulating sleep promotion, wakefulness, and attention may contribute to new insights regarding the core impairments in ADHD and lead to the development of new therapies.

Publisher

SAGE Publications

Subject

Clinical Psychology,Developmental and Educational Psychology

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