Longitudinal Stability of Neural Correlates of Pediatric Attention Deficit Hyperactivity Disorder: A Pilot Study of Event Related Potentials and Electroencephalography-Reference-Cited by-同舟云学术

Longitudinal Stability of Neural Correlates of Pediatric Attention Deficit Hyperactivity Disorder: A Pilot Study of Event Related Potentials and Electroencephalography

Published:2023-12-28 Issue:4 Volume:28 Page:493-511
ISSN:1087-0547
Container-title:Journal of Attention Disorders
language:en
Short-container-title:J Atten Disord

Author:

Peisch Virginia¹²,Rutter Tara M.³^ORCID,Sargent Christina⁴,Oommen Rachel⁴,Stein Mark A.⁴,Arnett Anne B.¹²^ORCID

Affiliation:

1. Boston Children’s Hospital, MA, USA

2. Harvard Medical School, Boston, MA, USA

3. Oregon Health and Sciences University, Portland, USA

4. University of Washington, Seattle, USA

Abstract

Objective: Stability and developmental effects of electroencephalography (EEG) and event related potential (ERP) correlates of ADHD are understudied. This pilot study examined stability and developmental changes in ERP and EEG metrics of interest. Methods: Thirty-seven 7 to 11-year-old children with ADHD and 15 typically developing (TD) children completed EEG twice, 11 to 36 months apart. A series of mixed effects linear models were run to examine stability and developmental effects of EEG and ERP metrics. Results: Stability and developmental effects of EEG and ERP correlates of ADHD varied considerably across metrics. P3 amplitude was stable over time and showed diverging developmental trajectories across groups. Developmental differences were apparent in error related ERPs and resting aperiodic exponent. Theta-beta ratio was stable over time among all children. Conclusions: Developmental trajectories of EEG and ERP correlates of ADHD are candidate diagnostic markers. Replication with larger samples is needed.

Funder

National Institute of Mental Health

Klingenstein Third Generation Foundation

Publisher

SAGE Publications

Subject

Clinical Psychology,Developmental and Educational Psychology

Link

http://journals.sagepub.com/doi/pdf/10.1177/10870547231214983

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