Mothers’ ability to determine and measure paracetamol doses for children—a contrived observational study

Author:

Prasadi GAM12ORCID,Senarathna L134,Dharmaratne SD567,Mohamed F18910,Jayasinghe SS11,Dawson A11213

Affiliation:

1. South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

2. Department of Pharmacy, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka

3. Department of Health Promotion, Faculty of Applied Sciences, Rajarata University, Mihintale, Sri Lanka

4. School of Public Health of the University of Sydney, Sydney, NSW, Australia

5. Department of Community Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

6. Department of Health Metrics Sciences, Institute for Health Metrics and Evaluation, School of Medicine, University of Washington, USA

7. Department of Family and Community Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA

8. Department of Pharmacy, Faculty of Allied Health Sciences, University of Peradeniya, Peradeniya, Sri Lanka

9. Faculty of Medicine and Health, Biomedical informatics and Digital Health, Clinical Pharmacology and Toxicology Research Group, University of Sydney, Sydney, NSW, Australia

10. National Poison Centre, Universiti Sains Malaysia, Penang, Malaysia

11. Department of Pharmacology, Faculty of Medicines, University of Ruhuna, Galle, Sri Lanka

12. Central Clinical School, University of Sydney, Sydney, NSW, Australia

13. New South Wales Poisons Information Centre, Sydney Children’s Hospital Network, Sydney, Australia

Abstract

Caregivers are primarily responsible for the administration of Over The Counter (OTC) medications in children. This study examines the mothers’ ability to determine and measure paracetamol doses for children aged between 1 and 5 years. A contrived observational study was conducted for mothers of preschool aged children at two Public Health Midwifery (PHM) areas in Southern province, Sri Lanka. Stratified random sampling was used. Only 26.9% ( n = 95, 95% CI = 22.5%–31.7%) of the 353 participants correctly determined and measured the doses of paracetamol. Errors were frequently made in both determining and measuring dose together ( n = 113, 32.0%, 95% CI = 27.3%–37.1%), determining only ( n = 94, 26.6%, 95% CI = 22.2%–31.5%) and measurement only ( n = 51, 14.4%, 95% CI = 11.1%–18.5%). Dose determined errors were not significantly associated with maternal education, number of children in the family, total monthly income and age of the index child. Similarly measuring errors were not significantly associated with mothers’ education, income of the family and number of children in the family. However, there was a weak positive correlation between measuring errors and age of the index child. The study suggests that mothers made errors when determining doses and measuring doses of paracetamol. Results emphasize importance of clear, concise guardian information leaflet and healthcare professionals’ guidance to minimize dosing errors of child medication.

Funder

NHMRC Project

Publisher

SAGE Publications

Subject

Pediatrics,Pediatrics, Perinatology and Child Health

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