Synthesis and Anti-Human Immunodeficiency virus Type 1 Activity of Novel 3′-Spiro Nucleoside Analogues of TSAO-T
Author:
Affiliation:
1. Instituto de Química Médica (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain
2. Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium
Publisher
SAGE Publications
Link
http://journals.sagepub.com/doi/pdf/10.1177/095632029700800604
Reference32 articles.
1. 1,2,3-Triazole-[2,5-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) (TSAO) Analogs: Synthesis and Anti-HIV-1 Activity
2. 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
3. [2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1
4. TSAO derivatives: highly specific human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors
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