Synthesis of 2′,3′,5′-trideoxyuridine-5′-methylphosphonic Acid and its Diphosphate Derivative. Study of the Interaction with HIV-1 reverse Transcriptase
Author:
Affiliation:
1. Université Montpellier II, URA 488 du CNRS, Place E. Bataillon, 34095 Montpellier Cedex 5, France
2. Abteilung Biophysik, Max-Planck Institut für medizinische Forschung, Jahnstrasse 29, 69028 Heidelberg, Germany
Abstract
Publisher
SAGE Publications
Link
http://journals.sagepub.com/doi/pdf/10.1177/095632029400500403
Reference25 articles.
1. Synthesis of a Phosphonomethyl Analogue of 3'-Deoxy-3'-fluorothymidine.
2. Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity
3. Kinetics of interaction of HIV reverse transcriptase with primer/template
4. 3'-Azido-3',5'-dideoxythymidine-5'-methylphosphonic acid diphosphate: synthesis and HIV-1 reverse transcriptase inhibition.
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1. Design, Synthesis, and Antiviral Activity of Adenosine 5‘-Phosphonate Analogues as Chain Terminators against Hepatitis C Virus;Journal of Medicinal Chemistry;2005-03-15
2. Pyrophosphoryl Derivatives of 1-(2-Deoxy-3-O-Phosphonomethyl-β-and-α-D-Erythro-Pentofuranosyl)Thymine: Synthesis and Substrate Properties Towards Some DNA Polymerases;Nucleosides, Nucleotides and Nucleic Acids;2000-10
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