Comparison of antibacterial property of herbal plant–based bio-active extract loaded polymer electrospun nanofibrous mat wound dressings

Abstract

Treating wound is challenging if there is microbial colonization. In this paper, we tried to review comparison of bacterial inhibition zone of different herbal plant bioactive loaded polymer electrospun nanofibrous wound dressings. A systematic literature search called preferred reporting items for systematic reviews and meta-analyses (PRISMA) was used to review bacterial inhibition zone of the different herbal plant bioactive loaded polymer electrospun nanofibrous mats used for wound dressing applications. The literatures were searched from PubMed, Scopus, Web of Science, and Google Scholar databases published in English from 2010 to 2021. Two hundred articles were searched out; from these, 93 articles are selected and studied their bacterial inhibition zone, among them eight have the highest bacterial inhibition zone greater than or equal to 20 mm. From the studied plant bioactive extract loaded polymer electrospun nanofibrous mat wound dressings, PVA/ Tridax procumbensviz have the highest antibacterial property (42 mm and 35 mm bacterial inhibition zone to Staphylococcus aureus and Escherichia coli, respectively). The second highest antibacterial property is PVA /honey/Curcuma longa with bacterial inhibition zone of 38 mm to S. aureus and the third one is PCL/carboxyethyl chitosan/PVA/ Matricaria chamomile L. with an inhibition zone of 37.5 mm to E. coli bacteria.