The differential effects of flumazenil on the psychomotor and amnesic actions of midazolam-Reference-Cited by-同舟云学术

The differential effects of flumazenil on the psychomotor and amnesic actions of midazolam

Published:1990-01 Issue:1 Volume:4 Page:29-34
ISSN:0269-8811
Container-title:Journal of Psychopharmacology
language:en
Short-container-title:J Psychopharmacol

Author:

Birch Brian¹,Curran H. Valerie²

Affiliation:

1. Departments of Minimally Invasive Surgery, Royal Northern Hospital, Holloway Road, London N7 and Institute of Urology, Shaftesbury Avenue, London WC2

2. Department of Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, U.K.

Abstract

Forty-four patients given midazolam prior to day-care urological surgery had the benzodiazepine antagonist, flumazenil, or placebo administered postoperatively. Flumazenil reversed the psychomotor impairments induced by midazolam but not its amnesic effects. There was no evidence of resedation for up to 6 h following the use of flumazenil.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology

Link

http://journals.sagepub.com/doi/pdf/10.1177/026988119000400105

Reference20 articles.

1. The role of midazolam and flumazenil in urology

2. Tranquillising memories: A review of the effects of benzodiazepines on human memory

3. Differential amnesic properties of benzodiazepines: a dose-response comparison of two drugs with similar elimination half-lives

4. The effects of single doses of alpidem and lorazepam on memory and psychomotor performance in normal humans

5. RO 15-1788 antagonises the central effects of diazepam in man without altering diazepam bioavailability.

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