Olanzapine treatment in Jarisch-Herxheimer reaction due to neurosyphilis with dementia: a case report

Author:

Ates MA1,Algul A.2,Gecici O.3,Semiz UB2,Yilmaz O.2,Gulsun M.4

Affiliation:

1. Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey,

2. Department of Psychiatry, GATA Haydarpasha Training Hospital, Istanbul, Turkey

3. Department of Psychiatry, Medicine School, Afyon Kocatepe University, Afyon, Turkey

4. Department of Psychiatry, Isparta Military Hospital, Isparta, Turkey

Abstract

We discussed a neurosyphilis case who had a risky sexual intercourse history nearly 10 years ago. After the neurosyphilis diagnosis, the patient has clinical symptoms of a demential case starting as a typical manic episode and Jarisch-Herxheimer reaction because of intravenous penicillin treatment that has improved with olanzapine treatment.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology

Reference9 articles.

1. Neurosyphilis – a Treatable Psychosis

2. Cytokines involved in human septic shock--the model of the Jarisch- Herxheimer reaction

3. La neurosyphilis : une cause rare de démence

4. Schmidt, RP ( 1992) Neurosyphylysis. In: Joynt, RJ (ed), Clinical Neurology, vol. 2. Philadelphia: JB Lippincott Company, Revised Edition: 1-23 (Chapter 28).

5. A case of neurosyphilis with a florid Jarisch–Herxheimer reaction

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