Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases-Reference-Cited by-同舟云学术

Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases

Published:2008-06-18 Issue:6 Volume:23 Page:723-726
ISSN:0269-8811
Container-title:Journal of Psychopharmacology
language:en
Short-container-title:J Psychopharmacol

Author:

Akkaya C¹,Kaya B²,Kotan Z²,Sarandol A²,Ersoy C³,Kirli S²

Affiliation:

1. Medical Faculty, Psychiatry Department, Uludag University, Bursa, Turkey

2. Medical Faculty, Psychiatry Department, Uludag University, Bursa, Turkey

3. Medical Faculty, Endocrinology Department, Uludag University, Bursa, Turkey

Abstract

Abstract Schizophrenia is a chronic and debilitating psychotic mental disorder that affects about 1% of the world's population. Antipsychotic drugs are the mainstay of treatment in schizophrenia. Hyperprolactinemia, which is a common side effect of typical antipsychotics, is also associated with the use of some of the newer atypical agents. Antipsychotics may enhance prolactinoma growth as manifested by an increase in serum prolactin concentration. Prolactin-secreting pituitary adenomas possibly related with antipsychotics have been described in the literature. To our knowledge, this is the first series of cases showing a possible relation between pituitary adenomas and amisulpride treatment in patients with schizophrenia.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0269881108091252

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3. Schizophrenia

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