Anxiety - bridging the heart/mind divide-Reference-Cited by-同舟云学术

Anxiety - bridging the heart/mind divide

Published:2009-04-03 Issue:5 Volume:24 Page:633-638
ISSN:0269-8811
Container-title:Journal of Psychopharmacology
language:en
Short-container-title:J Psychopharmacol

Author:

Davies SJC¹,Esler M.²,Nutt DJ³

Affiliation:

1. Psychopharmacology Unit, University of Bristol, Bristol, UK,

2. Baker Heart Research Institute, Melbourne, Australia

3. Psychopharmacology Unit, University of Bristol, Bristol, UK

Abstract

Although the complimentary roles of heart and brain in anxiety have been recognised for centuries, the precise contribution of each and more importantly perhaps their interplay has proved difficult to describe. Recent data from human brain imaging and cardiovascular physiology studies are beginning to delineate the mechanistic pathways of anxiety disorders in general and panic in particular. Evidence for a dysfunction of brain gamma-amino butyric acid-A and serotonin (5HT) systems in both panic and cardiovascular regulation is reviewed along with new evidence for altered sympathetic nervous system activity in the heart and periphery. Testable hypotheses and research ideas are suggested.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0269881109103800

Reference54 articles.

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