A review of COVID-19 therapeutics in pregnancy and lactation-Reference-Cited by-同舟云学术

A review of COVID-19 therapeutics in pregnancy and lactation

Published:2022-01-12 Issue:4 Volume:15 Page:225-232
ISSN:1753-495X
Container-title:Obstetric Medicine
language:en
Short-container-title:Obstet Med

Author:

Jorgensen Sarah CJ¹²^ORCID,Tabbara Najla²^ORCID,Burry Lisa¹²³

Affiliation:

1. Institute of Medical Science, Faculty of Medicine, University of Toronto, ON, Canada

2. Department of Pharmacy, Mount Sinai Hospital, Toronto, ON, Canada

3. Leslie Dan Faculty of Pharmacy, University of Toronto, ON, Canada

Abstract

Pregnant people have an elevated risk of severe COVID-19-related complications compared to their non-pregnant counterparts, underscoring the need for safe and effective therapies. In this review, we summarize published data on COVID-19 therapeutics in pregnancy and lactation to help inform clinical decision-making about their use in this population. Although no serious safety signals have been raised for many agents, data clearly have serious limitations and there are many important knowledge gaps about the safety and efficacy of key therapeutics used for COVID-19. Moving forward, diligent follow-up and documentation of outcomes in pregnant people treated with these agents will be essential to advance our understanding. Greater regulatory push and incentives are needed to ensure studies to obtain pregnancy data are expedited.

Publisher

SAGE Publications

Subject

Obstetrics and Gynecology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1753495X211056211

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