Digital pathology world tour

Author:

Rizzo Paola Chiara1,Caputo Alessandro2,Maddalena Eddy3,Caldonazzi Nicolò1,Girolami Ilaria45,Dei Tos Angelo Paolo6,Scarpa Aldo1,Sbaraglia Marta6,Brunelli Matteo1,Gobbo Stefano7,Marletta Stefano89,Pantanowitz Liron10,Della Mea Vincenzo3,Eccher Albino11ORCID

Affiliation:

1. Department of Pathology and Diagnostics and Public Health, Section of Pathology, University Hospital of Verona, Verona, Italy

2. Department of Medicine and Surgery, University of Salerno, Fisciano, Italy

3. Department of Mathematics, Computer Science and Physics, University of Udine, Udine, Italy

4. Department of Pathology, Provincial Hospital of Bolzano (SABES-ASDAA), Bolzano-Bozen, Italy

5. Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversität, Bolzano, Italy

6. Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy

7. Department of Translational Medicine, University of Ferrara, Ferrara, Italy

8. Department of Pathology, Pederzoli Hospital, Peschiera del Garda, Verona, Italy

9. Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy

10. Department of Pathology, University of Michigan, Ann Arbor, MI, USA

11. Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy

Abstract

Objective Digital pathology (DP) is currently in the spotlight and is rapidly gaining ground, even though the history of this field spans decades. Despite great technological progress, the adoption of DP for routine clinical diagnostic use remains limited. Methods A systematic search was conducted in the electronic databases Pubmed-MEDLINE and Embase. Inclusion criteria were all published studies that encompassed any application of DP. Results Of 4888 articles retrieved, 4041 were included. Relevant articles were categorized as “diagnostic” (147/4041, 4%) where DP was utilized for routine diagnostic workflow and “non-diagnostic” (3894/4041, 96%) for all other applications. The “non-diagnostic” articles were further categorized according to DP application including “artificial intelligence” (33%), “education” (5%), “narrative” (17%) for reviews and editorials, and “technical” (45%) for pure research publications. Conclusion This manuscript provided temporal and geographical insight into the global adoption of DP by analyzing the published scientific literature.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

SAGE Publications

Subject

Health Information Management,Computer Science Applications,Health Informatics,Health Policy

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