Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman-Reference-Cited by-同舟云学术

Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman

Published:2013-09-06 Issue:14 Volume:22 Page:1523-1525
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Fließer EE¹,Korsten P¹,Koziolek MJ¹,Niewold TB²,Patschan D¹,Müller GA¹,Patschan SA¹

Affiliation:

1. Department of Nephrology and Rheumatology, University Medicine Göttingen, Göttingen, Germany

2. Division of Rheumatology and Department of Immunology, Mayo Clinic, Rochester, MN, USA

Abstract

We report the case of a 19-year-old woman with progressive proliferative lupus nephritis (LN) class III after induction and maintenance therapy with mycophenolate mofetil (MMF). Despite a satisfying clinical improvement proteinuria progressed under this medication. We treated the patient with additional belimumab after discussing other options. Following treatment with belimumab, proteinuria rapidly improved to almost normal levels and clinical remission lasted. Belimumab might hold promise for this indication.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0961203313504145

Reference8 articles.

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