Relationship of IL-2, IL-2R (CD25+), Soluble IL-2R and IL-4 with Disease Activity in SLE Patients-Reference-Cited by-同舟云学术

Relationship of IL-2, IL-2R (CD25+), Soluble IL-2R and IL-4 with Disease Activity in SLE Patients

Published:1993-08 Issue:4 Volume:2 Page:257-260
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Cuadrado Maria J.¹,Marubayashi Miriam²,Ortega Consuelo²,Fernandez-Arcas Nieves²,Garcia-Cozar Francisco²,Pena Jose²,Sanchez-Guijo Pedro³,Santamaria Manuel²

Affiliation:

1. Unit of Rheumatology, Hospital Universitario Reina Sofia, Facultad de Medicina, Universidad de Cordoba, 14004 Cordoba, Spain

2. Unit of Immunology, Hospital Universitario Reina Sofia, Facultad de Medicina, Universidad de Cordoba, 14004 Cordoba, Spain

3. Unit of Internal Medicine, Hospital Universitario Reina Sofia, Facultad de Medicina, Universidad de Cordoba, 14004 Cordoba, Spain

Abstract

The plasma levels of interleukin-4 (IL-4), interleukin-2 (IL-2), soluble receptor of IL-2 (IL-2R) and T cell expression of IL-2 receptor chain (CD25+) were determined in an attempt to relate these parameters with disease activity in systemic lupus erythematosus (SLE). IL-4, IL-2 and sIL-2R plasma levels of SLE patients were significantly higher than those of the control group (P<0.05) while CD25+expression was similar in both groups. Only sIL-2R levels were significantly higher (P<0.05) in active than in inactive patients.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/096120339300200409

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