Development of anti-Sm and anti-DNA antibodies followed by clinical manifestation of systemic lupus erythematosus in an elderly woman with long-standing Sjögren's syndrome-Reference-Cited by-同舟云学术

Development of anti-Sm and anti-DNA antibodies followed by clinical manifestation of systemic lupus erythematosus in an elderly woman with long-standing Sjögren's syndrome

Published:1995-02 Issue:1 Volume:4 Page:63-65
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Satoh Minoru¹,Yamagata Hajime¹,Watanabe Fumie¹,Nakayama Shoji¹,Ogasawara Takashi²,Tojo Takeshi²,Akizuki Masashi²

Affiliation:

1. Department of Internal Medicine, National Murayama Hospital

2. Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

Abstract

A 69-year-old Japanese women who had been followed up for 10 years as a primary Sjögren's syndrome, is reported. She suddenly developed serological and clinical characteristics of systemic lupus erythematosus (SLE): anti-Sm and anti-dsDNA antibodies followed by nephrotic syndrome and pancytopenia. This case suggests that the diagnosis of primary Sjögren's syndrome should be considered as tentative in certain cases and that the development of serological characteristics precede and are associated with the development of clinical symptoms of SLE.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/096120339500400113

Reference10 articles.

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2. Primary Sjogren's syndrome preceding the presentation of systemic lupus erythematosus as a benign intracranial hypertension syndrome.

3. Association of Antibodies to Ribonucleoprotein and Sm Antigens with Mixed Connective-Tissue Disease, Systemic Lupus Erythematosus and Other Rheumatic Diseases

4. Antinuclear Antibodies: Diagnostic Markers for Autoimmune Diseases and Probes for Cell Biology

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