Ultraviolet light and cutaneous lupus-Reference-Cited by-同舟云学术

Ultraviolet light and cutaneous lupus

Published:2006-11 Issue:11 Volume:15 Page:724-727
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Bijl Marc¹,Kallenberg Cees GM²

Affiliation:

1. Department of Internal Medicine, Division of Clinical Immunology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands

2. Department of Internal Medicine, Division of Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Abstract

Exposure to ultraviolet (UV) light is one of the major factors known to trigger cutaneous disease activity in (systemic) lupus erythematosus patients. UV light, UVB in particular, is a potent inducer of apoptosis. Currently, disturbed clearance of apoptotic cells is one of the concepts explaining the development of inflammation in lupus patients. We review the role of apoptotic cells and autoantibodies in the pathogenesis of UVB induced skin lesions.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0961203306071705

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