Unilateral facial erythematous patch as the presenting sign of systemic lupus erythematosus

Author:

Ha Dae-Lyong12ORCID,Lee Gi-Wook12,Shin Kihyuk13,Kim Hoon-Soo12,Ko Hyun-Chang13,Kim Byung-Soo12,Kim Moon-Bum12

Affiliation:

1. Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea

2. Biomedical Research Institute, Pusan National University Hospital, Busan, Korea

3. Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, Korea

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that can have many cutaneous manifestations including malar rash, discoid rash or oral ulcer. Isolated unilateral involvement of face is uncommon in SLE. It lacks typical clinical features of LE, and may impose a diagnostic challenge for clinicians. Herein we report a case of 62-year-old woman presenting with a 2-year history of erythematous patches on left cheek and eyelid. Initially, she was diagnosed as having recurrent blepharitis or cellulitis that did not respond to conventional treatment with ophthalmic medicaments. As time went by, the patches spread to her left cheek, and she was referred to our dermatologic department. Histopathologic examination was consistent with LE. Further physical and laboratory tests have found that she had oral ulcers, proteinuria, thrombocytopenia and abnormal titer of anti-nuclear antibody satisfying the diagnosis of SLE. From this case, we think unilateral erythematous patches on face could be a rare manifestation of SLE and more intention should be paid to this type of patients, because unilateral facial symptom may mimic other dermatoses.

Publisher

SAGE Publications

Subject

Rheumatology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Unilateral facial actinic elastotic plaque: A distinct but underreported manifestation of solar elastosis;Journal of the European Academy of Dermatology and Venereology;2022-11-04

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