Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil

Author:

Ungprasert P1,Chowdhary V R1,Davis M D2,Makol A1

Affiliation:

1. Division of Rheumatology, Mayo Clinic, Rochester, USA

2. Department of Dermatology, Mayo Clinic, Rochester, USA

Abstract

Hematological abnormalities, such as anemia, leucopenia, and thrombocytopenia, secondary to peripheral destruction, are common in systemic lupus erythematosus (SLE). However, cytopenias from autoimmune myelofibrosis (AIMF) are extremely uncommon in SLE, with less than 40 reported cases in the literature. We report the case of a 33-year-old female who presented with bullous skin lesions and pancytopenia as the presenting manifestation of what was ultimately diagnosed as SLE with AIMF. She responded well to glucocorticoids and mycophenolate mofetil.

Publisher

SAGE Publications

Subject

Rheumatology

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