Acute acalculous cholecystitis in juvenile systemic lupus erythematosus

Author:

Mendonça JA1,Marques-Neto JF2,Prando P1,Appenzeller S3

Affiliation:

1. Rheumatology Service, Hospital Vera Cruz, Campinas, Sao Paulo, Brazil

2. Rheumatology Service, Hospital Vera Cruz, Campinas, Sao Paulo, Brazil; Rheumatology Unit, Department of Internal Medicine, State University of Campinas Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil

3. Rheumatology Unit, Department of Internal Medicine, State University of Campinas Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil

Abstract

Small- and medium-vessel vasculitis is a common manifestation in systemic lupus erythematosus (SLE) and may occur in any organ. However, acute acalculous cholecystitis is a rare abdominal manifestation in SLE, especially in children. We report a case of a 12-year-old patient who initially presented with AAC and seizure. Follow-up investigation diagnosed SLE, and brain magnetic resonance imaging had hyperintense white matter lesions in cortico-subcortical regions. The patient was successfully treated with pulse methylprednisolone and cyclophosphamide without surgical intervention.

Publisher

SAGE Publications

Subject

Rheumatology

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